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Single-molecule Magnetic Tweezer Tests On DNABiomedical researchers stretch and twist single DNA molecules with magnetic tweezers. By making the molecule writhe into a plectoneme (ply), DNA parameters, such as its effective radius, are estimated. Adding untangling enzymes (topoisomerases) to the DNA's environment, their individual cuts are detected as jumps in extension.
Socializing Can Help Elderly Women Stay SharpSocializing with friends and family can do more than lift the spirits of elderly women it can improve cognition and might help prevent dementia, according to a new study.The study began in 2001 and included women at least 78 years old who were free of signs of dementia. Researchers conducted follow-up interviews between 2002 and 2005.
Armed Forces Multi-Million Dollar Effort To Help SoldiersA procedure currently performed all over the world for cosmetic purposes might also improve wound healing and limb function for soldiers who are severely hurt and scarred during combat. Dr. Adam Katz, plastic surgeon and researcher at the University of Virginia Health System, will conduct research in this area under the Armed Forces Institute of Regenerative Medicine (AFIRM). White House officials announced the formation of AFIRM, which has received more than $80 million for research.
Amicus Therapeutics Begins Phase 2 Clinical Trial Of AT2220 In Pompe DiseaseAmicus Therapeutics (Nasdaq: FOLD), a biopharmaceutical company developing small molecule, orally-administered pharmacological chaperones for the treatment of human genetic diseases, today announced that it has initiated a Phase 2 clinical trial of AT2220 (1-deoxynojirimycin HCl), for the treatment of Pompe disease.
Mouse Ovaries And Testes Age In Unique WaysAging leads to large changes in gene activity in the ovaries of mice, but only limited changes in testes, according to research published in the open-access journal, BMC Biology. A lifespan-extending calorie-restricted diet reversed some of the aging effects - but, unlike the widespread changes observed in somatic organs, it had an impact only in a small number of gonad-specific genes.
Aggression, Sex And Individual Differences In Cerebral Lateralization In A Cichlid FishCerebral lateralization, handling different tasks with one particular side of the brain or the other, seems ubiquitous among vertebrates. Individuals within a species show considerable variation in lateralization. Why such variation exists is unknown. It is known that individuals with more strongly lateralized brains are at an advantage in tasks such as those involving multitasking.
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